While a lot of people with Brugada syndrome do now not have any signs and symptoms, Brugada syndrome may additionally cause fainting or surprising cardiac dying due to extreme bizarre coronary heart rhythms which includes ventricular traumatic inflammation or polymorphic ventricular tachycardia. Blackouts can be as a result of quick strange heart rhythms that revert to a ordinary rhythm spontaneously. If a risky coronary heart rhythm does not stop with the aid of itself and is left untreated, the individual may additionally have a fatal cardiac arrest. However, blackouts can occur in those with Brugada syndrome in spite of a regular coronary heart rhythm because of a sudden drop in blood stress, called vasovagal syncope.
The strange coronary heart rhythms visible in Brugada syndrome frequently occur at relaxation, following a heavy meal, or even at some stage in sleep. These conditions are connected to durations when the vagus nerve is activated, called durations of excessive vagal tone. Abnormal coronary heart rhythms may additionally arise throughout fever or following excessive alcohol. Sodium channel blocking off medicinal drugs, commonly used to treat cardiac arrhythmia, can also worsen the tendency to ordinary coronary heart rhythms in sufferers with Brugada syndrome and have to be prevented.