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Since then, a range of various herbal matrices were examined for his or her usefulness as an artificial ovary. Included in those are fibrin, alginate and decellularized human ovary that have proven in vitro maturation, ovary-like shape production and the production of offspring whilst transplanted into mice. In addition to those activities being determined one by one, the overall process of development from the grafting of preantral follicles to the ovary via to the beginning of live offspring has been confirmed within the mouse version.