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There are two fundamental instructions of membrane lipids: glycerophospholipids and sphingolipids. Although many exceptional membrane lipids are synthesized in our body, pathways proportion the identical pattern. The first step is synthesizing the spine (sphingosine or glycerol), the second step is the addition of fatty acids to the spine to make phosphatidic acid. Phosphatidic acid is in addition modified with the attachment of various hydrophilic head agencies to the spine. Membrane lipid biosynthesis occurs within the endoplasmic reticulum membrane.