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Regionally developed ecotypes may be threatened with extinction whilst new alleles or genes are introduced that alter that ecotype. This is occasionally referred to as genetic mixing. Hybridization and introgression, that could occur in natural and hybrid populations, of recent genetic cloth can cause the replacement of neighborhood genotypes if the hybrids are greater suit and have breeding blessings over the indigenous ecotype or species. These hybridization events can end result from the advent of non-native genotypes with the aid of human beings or thru habitat change, bringing formerly isolated species into contact. Genetic mixing can be especially negative for uncommon species in remoted habitats, in the end affecting the populace to this sort of diploma that none of the in the beginning genetically awesome population remains.