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• Comparing height to traditional increase charts.

• Determining the Tanner degree of sexual development. (Males with KS/CHH are usually at degree I or II with genitalia, females at degree I with breast development and both women and men at stage III with pubic hair improvement).

• Checking for micropenis and undescended testes (cryptorchidism) in adult males.

• Measuring testicular extent.

• Checking for breast development and age at menarche in women.

• Checking sense of smell the usage of odorant panel or University of Pennsylvania Smell Identification Test (UPSIT)

• Checking for hearing impairment.

• Checking for missing tooth or presence of cleft lip and/or cleft palate.

• Checking for pigmentation of skin and hair.

• Checking for replicate moves of the arms or symptoms of neurodevelopmental put off.