Levels of oleic acid together with other MUFAs in red blood cellular membranes were positively related to breast most cancers chance. The saturation index (SI) of the equal membranes changed into inversely related to breast most cancers chance. MUFAs and low SI in erythrocyte membranes are predictors of postmenopausal breast most cancers. Both of those variables rely upon the activity of the enzyme delta-nine desaturase (Δ9-d).
Results from observational medical trials on PUFA intake and cancer had been inconsistent and range by means of numerous elements of cancer prevalence, such as gender and genetic chance. Some studies have shown institutions among higher intakes and/or blood tiers of omega-three PUFAs and a decreased threat of sure cancers, together with breast and colorectal cancer, at the same time as different studies determined no associations with cancer threat.